View source for Low dose of caffeine enhances the efficacy of antidepressants in major depressive disorder and the underlying neural substrates. - PubMed - NCBI

{{B|
https://www.ncbi.nlm.nih.gov/pubmed/28054436
|Low dose of caffeine enhances the efficacy of antidepressants in major depressive disorder and the underlying neural substrates. - PubMed - NCBI
|5
|5
}}
{{#set:
k=melancholy, caffeine, nootropics, antidepressants, depression, productivity, study, research
|+sep=, }}

[[Category: Mental health]]
[[Category: Pharmacology]]
[[Category: Productivity]]
[[Category: Studies]]
[[Category: Melancholy]]

A total of 95 male inpatients were assigned to three groups and were asked to take either '''caffeine (60, 120mg)''' or placebo (soymilk powder) daily for 4 weeks on the basis of their current antidepressant medications. Results showed that chronic supplementation with low dose of caffeine '''(60 mg) produced rapid antidepressant action''' by reduction of depressive scores. Furthermore, low dose of caffeine '''improved cognitive performance in depressed patients'''.